While you can vaccinate the dog against a variety of diseases, you cannot give the rabies vaccine. The rabies vaccine must always be given by a veterinarian. [2] X Research source

Most vaccines for animals are given just below the skin (subcutaneously) to reduce pain and possible reactions. If your pet has ever had a reaction to a vaccine, no matter how minor, do not attempt to give a vaccine of any type at home in case of a severe reaction.

The vaccine does not actually infect the dog, it only imitates the virus or bacteria, though the dog might have a slight reaction (like mild rash or fever).

Each vaccination has its own timeline, so talk with the vet to determine the timing of vaccinations for your pet. [6] X Research source

Most vaccines will need to be stored at normal refrigeration temperatures. Make sure you use a new needle that’s sharp when you give the vaccine. [8] X Expert Source Ray Spragley, DVMVeterinarian Expert Interview. 19 August 2021.

Unlike humans, you don’t need to prepare the site with an alcohol wipe.

If you see blood in the needle, you will need to find another location to give the injection. Blood in the needle means you’ve hit a blood vessel and you cannot give a vaccine into a blood vessel.

Never put an uncapped needle into the garbage since people who work at landfills could get injured.