Avoid screwing the applicator and the tube too tight. You’ll need to be able to get the tube of cream out of the applicator for future use.

You should be somewhat comfortable and have easy access to your vaginal opening.

It may help to point the applicator towards the small of your back when you place it into your vaginal opening.

Since some of the cream may leak out, you might want to wear a sanitary pad (not a tampon) to collect any discharge.

If you miss a dose or run out of the vaginal cream before your treatment is complete, call the doctor or pharmacist for a refill.

It’s best to store most medications in a cool, dry place. Avoid storing medication in a medicine cabinet since heat and moisture from the bathroom could cause it to be less effective or expire early. [1] X Research source

If you need to use vaginal creams during the day, wear a sanitary pad to avoid staining your underwear and lay down for a few minutes immediately after you apply the cream, if you can.

Be sure to read the information that came with the vaginal cream. This will give you more detailed information about the specific side effects you can expect.

Always ask your doctor if you have any questions about using the vaginal cream. You should also talk with your doctor about whether or not you need to refrain from sexual intercourse while you use the vaginal cream.